By Travis Johnson

There are many reasons to be excited for Annihilation, the adaptation of Jeff VanderMeer’s acclaimed novel from Alex Garland (Ex Machina, Sunshine), not least of which is that it boasts a largely female cast – aside from OScar Isaac, who plays Portman’s missing husband, the principal characters are all women.

In this new featurette, the female cast – Portman, Tessa Thompson, Jennifer Jason Leigh, Gina Rodriguez, and Tuva Novotny – expound on what an exciting and unusual prospect this is.

Annihilation hits Netflix in March.

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